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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
12.42
Human Site:
Y1125
Identified Species:
22.78
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
Y1125
Q
E
M
L
R
M
W
Y
E
L
D
E
E
S
R
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
Y1125
Q
E
M
L
R
M
W
Y
E
L
D
E
E
S
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
G1107
H
Q
I
L
K
M
W
G
E
L
D
E
Q
S
R
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
Y1132
Q
Q
M
L
Q
M
W
Y
D
L
D
E
E
S
R
Rat
Rattus norvegicus
O54889
1716
194174
H1132
Q
Q
M
L
Q
M
W
H
E
L
D
E
Q
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
P844
S
F
Y
S
G
L
T
P
T
E
F
F
F
H
T
Frog
Xenopus laevis
NP_001082182
1730
195193
Y1130
R
Q
V
L
E
S
W
Y
S
V
N
E
K
T
L
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
R1118
L
Q
L
I
E
R
W
R
A
L
D
E
S
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
R1092
I
N
S
K
T
G
R
R
R
F
D
E
G
L
L
Honey Bee
Apis mellifera
XP_001121092
1665
190473
V1075
S
G
R
S
K
A
A
V
S
Y
M
R
K
W
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
E1157
M
W
F
E
L
S
L
E
E
R
E
Q
Y
A
R
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
W1126
K
K
R
I
I
R
R
W
R
E
V
T
D
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
E1111
Y
R
K
K
H
S
K
E
P
H
Y
K
Q
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
60
N.A.
80
73.3
N.A.
N.A.
0
26.6
33.3
N.A.
13.3
0
13.3
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
100
100
N.A.
N.A.
6.6
73.3
53.3
N.A.
13.3
13.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
54
0
8
0
0
% D
% Glu:
0
16
0
8
16
0
0
16
39
16
8
62
24
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
8
8
8
8
0
0
% F
% Gly:
0
8
0
0
8
8
0
8
0
0
0
0
8
8
0
% G
% His:
8
0
0
0
8
0
0
8
0
8
0
0
0
8
8
% H
% Ile:
8
0
8
16
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
8
16
16
0
8
0
0
0
0
8
16
0
0
% K
% Leu:
8
0
8
47
8
8
8
0
0
47
0
0
0
8
16
% L
% Met:
8
0
31
0
0
39
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
31
39
0
0
16
0
0
0
0
0
0
8
24
0
0
% Q
% Arg:
8
8
16
0
16
16
16
16
16
8
0
8
0
8
54
% R
% Ser:
16
0
8
16
0
24
0
0
16
0
0
0
8
47
0
% S
% Thr:
0
0
0
0
8
0
8
0
8
0
0
8
0
8
8
% T
% Val:
0
0
8
0
0
0
0
8
0
8
8
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
54
8
0
0
0
0
0
8
0
% W
% Tyr:
8
0
8
0
0
0
0
31
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _